Title:Relationship of lipid profile and erythrocyte indices in non-anaemic elderly

Author:Mohammad Noori, Shima Azadpour, Ali Asghar Valipour, Somayeh Igder and Reza Malihi

Abstract:Objectives: Several human studies have reported a variety of morphologic alterations in erythrocyte in relation to serum lipid components in different pathological states, but there are few reports about the influence of lipid profiles on heamatologic parameters in healthy individuals. This study evaluated the effect of elevated serum level of the lipid indices on the alteration of the RBC indices in healthy elderly persons.
Methods: 275 non-anaemic elderly people were assessed for the association between dyslipidemia and circulating erythrocyte indices in the southwest of Iran. The student t-test and Chi-square test were used for statistical comparison.
Results: There was a statistically significant difference between elderly women with and without hypercholesterolemia and hypertriglyceridemia, and in age-matched men with regard to the red cell count, haemoglobin, and haematocrit (p<0.001) but not for mean cell volume (p>0.05). Fasting levels of LDL-C are significantly associated with erythrocyte number, hematocrit, and haemoglobin concentration (p<0.001) in healthy elderly men and women while HDL-C levels are only associated with re3d cell count (p<0.001) and haemoglobin (p<0.05).
Conclusions: We conclude that dyslipidemia appears to have a significant effect on red cell indices in non-anaemic elderly persons.
Key words: Dyslipidemias; erythrocyte indices; elderly, non-anaemic.

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