Title:Can the use of triglyceride to glucose and triglyceride to high density lipoprotein ratios indicate metabolic syndrome in the spinal cord injured male?

Author:Lynnette M Jones and Michael Legge

Abstract:Aim: To determine whether the use of triglyceride to glucose (TyG:G) and triglyceride to high density lipoprotein (TyG:HDL) indices can indicate the onset of metabolic syndrome in spinal cord injured (SCI) males.
Methods: Fasting plasma from 20, age, BMI, and physical parameters matched controls and 20 spinal cord injured males was analysed for triglycerides, glucose and insulin. In addition to the analyte values HOMA-IR was calculated for both groups.
Results: Significant differences were identified between spinal cord injured complete and incomplete injuries for the TyG:G (p=0.042) and TyG:HDL (p=0.037) when compared with matched controls. Complete spinal cord injured were significantly different for TyG:G (p=0.039) and TyG:HDL (p=0.001). Those with incomplete lesions were not significantly different from the matched controls TyG:G (p=0.871) and TyG:HDL (p=0353).
Conclusion: Those with complete spinal cord injuries demonstrated outcomes consistent with metabolic syndrome, whereas those with incomplete spinal cord injuries did not differ from the able-bodied controls. It is concluded that the level of de-innervation has a significant role in the onset of metabolic syndrome in the spinal cord injured.
Keywords: spinal cord injured (SCI)
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